Endocrine Abstracts

Objectives: To evaluate the effect of alendronate, alfacalcidol, and combinat agent of alendronate and alfacalcidol, in BMD change assess by Digital X-ray Radiogrammetry in postmenopausal women.Materials and methods: Nine thousand and two hundred and sixty four healthy women with ages between 20 and 89 years referred to our densitometry service using DXR-BMD. Six thousand and six hundred and twelve from these were in postmenopause. Using WHO-criteria for...

Hypovitaminosis D is frequent in population over 65 years age, producing a secondary hyperparathyroidism, increase the bone remodeling, bone loss and osteoporotic fractures, loss of the muscle force.Daily dose of 0.5 μg alfacalcidol was effectively in improved muscle strength in elderly and reduced falls. The bisphosphonates have been shown to increase Bone Mineral Density (BMD) and reduce bone turnover in postmenopausal osteoporosis. The combined a...